Sample Answer
Sepsis, Health Concepts, and Global Contexts
Introduction
Sepsis is a life‑threatening condition caused by the body’s dysregulated response to infection, leading to organ dysfunction and potentially death. It represents a critical intersection of social, political, economic and environmental challenges in healthcare systems globally. Understanding sepsis requires not only clinical insight, but also sensitivity to how concepts of health have evolved historically and philosophically, and how global structures influence its burden, prevention, and treatment. This essay addresses the definitions and dimensions of health in relation to sepsis (Task A), and then analyses sepsis through the lens of sustainable development, global health inequities, and political-economic issues (Task B), including a country comparison and evaluation of universal sepsis frameworks.
Task A: Definitions and Dimensions of Health, Issues & Debates around Sepsis
To analyse sepsis, it is useful to reflect on different concepts of health, because how we define “health” affects how we prioritise, prevent and treat sepsis.
Historical and Philosophical Concepts of Health
Historically, health was often understood simply as the absence of disease. Over time, this narrow biomedical model was challenged by broader philosophical conceptions. The World Health Organization’s (WHO) 1948 definition of health as “a state of complete physical, mental and social well‑being, not merely the absence of disease” reflects a shift toward a holistic and normative view of health.
Philosophically, there are debates around whether health is a descriptive concept (just biological functioning) or a normative one (involving value judgments). For example, some theorists argue for health as “normal functioning” (Boorse), whereas others view health in a broader “capability” framework (such as Sen’s capability approach), which emphasises what people are able to do and to be.
Dimensions of Health in Relation to Sepsis
When applied to sepsis, very practical debates arise. On the biomedical dimension, sepsis is clearly a severe physiological dysfunction. However, on the social dimension, determinants such as poverty, access to clean water or hygiene, and healthcare infrastructure are deeply relevant, especially in low‑ and middle‑income countries (LMICs). Politically and economically, inequalities in healthcare resources, antibiotic access, and public health systems shape who is vulnerable to sepsis and who receives timely care. Finally, from a global health ethics perspective, the high burden of sepsis in LMICs raises moral questions about justice, resource distribution, and the global responsibility to prevent avoidable deaths.
Thus, sepsis is not just a medical emergency, it is situated within a network of social, economic and political structures. Understanding the full dimension of sepsis’s impact requires grappling with these overlapping concepts of health.
Task B: Sepsis, SDGs, and Global Challenges
Approaches / Frameworks: Health & Sustainable Development Goals (SDGs)
To examine sepsis in a global context, it helps to use development frameworks, especially the Sustainable Development Goals (SDGs). Several SDGs are directly relevant to sepsis:
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SDG 3 (Good Health and Well-Being): Targets include reducing maternal mortality, ending preventable deaths of children, and achieving universal health coverage (UHC). Sepsis contributes heavily to maternal and neonatal deaths, especially in resource-limited settings.
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SDG 6 (Clean Water and Sanitation): Poor sanitation and lack of clean water contribute to infection risk, which can lead to sepsis.
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SDG 1 (No Poverty) & SDG 10 (Reduced Inequalities): Sepsis burden is disproportionately high in poorer populations and LMICs, where preventive and acute care resources are limited.
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SDG 17 (Partnerships for the Goals): Addressing sepsis globally requires cross-sector and international collaboration (governments, WHO, NGOs).
Using this SDG framework helps conceptualise sepsis not just as a clinical issue, but as a development and equity issue. The 2030 Global Agenda for Sepsis, for example, aligns with SDG 3 by calling for national action plans, early recognition systems, and improved data to reduce sepsis incidence and mortality.