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Understanding Long-Term Conditions (Type 2 Diabetes Mellitus)

Assignment Brief

To Enable Students to:
  • Demonstrate an in-depth knowledge of the underpinning anatomy, physiology and pathophysiology of a range of long term conditions.

  • Critically evaluate a range of theoretical perspectives which might be used to explain the effects of psychosocial influences which occur across the life span on the health status of adults in society.

  • Demonstrate an in-depth understanding of the health and social care needs of individuals with long term conditions, by integrating complex biopsychosocial information into the design of a range of appropriate and effective nursing interventions

Learning Outcomes:

  • Demonstrate an in-depth, systematic understanding of the pathophysiological changes that occur as a result of a range of long-term health problems

  • Critically analyse a range of communication strategies that might be used and adapted over time with patients who require continuing care.

  • Systematically examine the relationship between attitudinal development, belief systems, individual perception and response to health

  • Flexibly integrate an in-depth knowledge about the role of life events and lifestyles into an understanding of individuals and illness-specific trajectories of health and coping strategies.

Students will be able to:
  • Systematically address the current or future psychosocial needs of individuals and communities by assessing, planning, implementing and evaluating from a range of strategies which impact upon health.

  • Work flexibly in partnership with people to optimise the coping/self-care strategies and behaviours used by individuals to manage life stressors and health status.

  • Select appropriate strategies to monitor and attend to the pathophysiological and sociological status of the client/patient with chronic illness.

Sample Answer

Understanding Long-Term Conditions (Type 2 Diabetes Mellitus)

Introduction

Long-term conditions (LTCs) represent one of the most significant challenges facing contemporary health and social care systems. These conditions, which are typically chronic, progressive, and incurable, require lifelong management and coordinated care. Among these, Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent, with the World Health Organization (2023) reporting over 422 million global cases. In the United Kingdom, T2DM affects approximately 4.3 million people, accounting for a major public health concern (Diabetes UK, 2023). This essay critically analyses T2DM as a long-term condition by examining its pathophysiological mechanisms, psychosocial influences, communication strategies, and the integration of biopsychosocial approaches into effective nursing interventions. The discussion aims to demonstrate how complex physical and psychological processes shape the experiences and outcomes of individuals living with this condition.

Pathophysiology of Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus is a chronic metabolic disorder characterised by insulin resistance and impaired insulin secretion (Association of British Clinical Diabetologists, 2022). The pancreas initially compensates for insulin resistance by increasing insulin production; however, over time, β-cell dysfunction leads to decreased insulin output. This results in chronic hyperglycaemia, which disrupts glucose homeostasis and contributes to vascular complications.

At a cellular level, insulin resistance is often caused by defects in insulin receptor signalling in muscle, fat, and liver tissues. This reduces glucose uptake in skeletal muscle and increases hepatic glucose production, elevating blood sugar levels (DeFronzo, 2019). Obesity, particularly visceral adiposity, is a major contributing factor due to the secretion of pro-inflammatory cytokines such as tumour necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6), which impair insulin action.

Over time, sustained hyperglycaemia leads to microvascular and macrovascular complications including neuropathy, nephropathy, retinopathy, and cardiovascular disease (Chatterjee et al., 2017). These pathophysiological changes have profound implications for health and social care, as patients often experience functional decline, chronic pain, and reduced quality of life. Understanding these biological mechanisms is crucial for designing nursing interventions that target both physiological and behavioural aspects of disease management.

Psychosocial Influences Across the Lifespan

The psychosocial dimension of T2DM significantly affects disease trajectory and patient wellbeing. Psychological stress, socioeconomic status, cultural beliefs, and lifestyle habits interact to influence both the onset and management of the condition. According to the Health Belief Model (Rosenstock, 1974), individuals’ perceptions of susceptibility, severity, and benefits of action influence their engagement with health-promoting behaviours. In diabetes care, patients who underestimate the severity of the disease or perceive self-management as burdensome are less likely to adhere to dietary and medication regimens.

Across the lifespan, psychosocial influences vary. In early adulthood, lifestyle factors such as poor diet, sedentary behaviour, and work-related stress contribute to insulin resistance. In middle age, financial pressures and family responsibilities can exacerbate unhealthy habits. Older adults may face social isolation and depression, further complicating self-care (Katon et al., 2015). Studies show that people with T2DM are twice as likely to experience depression compared to the general population (Anderson et al., 2001), which can lead to poor glycaemic control through reduced motivation and adherence.

Socioeconomic inequalities also shape health outcomes. Individuals from lower-income backgrounds often experience barriers to accessing healthy foods, regular exercise, and medical support. Marmot (2010) argues that social determinants such as education, housing, and income are central to health inequality, suggesting that nursing practice must address these wider influences alongside clinical management.

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